Upstream Bio Inc.
UPB | NASDAQ
$5.37
+$0.03 (+0.56%)
At close: Sep 21, 2026, 4:00 PM ET
$5.37
$0 (-0.09%)
After-hours:
Sep 21, 2026, 7:30 PM ET
Company Profile
Upstream Bio, Inc. is a biotechnology company in the clinical development stage, dedicated to innovating therapies for inflammatory conditions, particularly those affecting the severe respiratory system. Its pipeline notably features verekitug, a monoclonal antibody designed to selectively target and suppress the thymic stromal lymphopoietin receptor. Beyond this, the company is actively developing treatments for severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Established in 2021, Upstream Bio maintains its operational base in Waltham, Massachusetts.
Key Executives
| Name | Position |
|---|---|
| E. Rand Sutherland | Chief Executive Officer & Director |
| Michael Paul Gray | Chief Financial Officer & Chief Operating Officer |
| Stacy Price | Chief Technology Officer |
| Aaron Deykin | Chief Medical Officer and Head of Research & Development |
| Adam Houghton | Chief Business Officer |
| Allison Ambrose | Senior Vice President, General Counsel & Secretary |
| Fang Xie | Vice President & Head of Biometrics |
| Lisa Fiering | Senior Vice President of People & Culture |
| Meggan Buckwell | Director of Corporate Communications & Investor Relations |
| Mersedeh Miraliakbari | Senior Vice President of Regulatory Affairs & Quality |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Sep 01, 2026 | 8-K | Current Report |
| Aug 12, 2026 | SC 13G/A | [Amend] Statement of acquisition of beneficial own... |
| Aug 11, 2026 | 10-Q | Quarterly Report |
| Aug 11, 2026 | 8-K | Current Report |
| Jul 30, 2026 | SC 13G | Statement of acquisition of beneficial ownership b... |
| Jun 17, 2026 | 4 | Filing |
| Jun 17, 2026 | 4 | Filing |
| Jun 17, 2026 | 4 | Filing |
| Jun 17, 2026 | 4 | Filing |
| Jun 17, 2026 | 4 | Filing |
Upstream Bio Inc.
| Country | United States |
| IPO Date | Oct 10, 2024 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 75 |
| CEO | E. Rand Sutherland |
Contact Details
890 Winter Street Waltham,
Massachusetts 02451 United States
Stock Details
| Ticker Symbol | UPB |
| Exchange | NASDAQ |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| CIK Code | 0002022626 |
| CUSIP Number | 91678A107 |
| ISIN Number | US91678A1079 |
| SIC Code | 2834 |
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