Upstream Bio Inc.

UPB | NASDAQ

Price Alert Chart Builder DCF Calculator

$5.37

+$0.03 (+0.56%)

At close: Sep 21, 2026, 4:00 PM ET

$5.37

$0 (-0.09%)

After-hours: Sep 21, 2026, 7:30 PM ET

Overview Rating Statistics Financials Earnings Analysts Ownership Profile

+0.56%

(1D)

Rating

Updated: Aug 13, 2026

Fundamentals Weak

Market Sentiment Neutral

Moat None

Full Analysis

Key Statistics

Market Data

Market Cap $291.96M

1D Range

5.28 5.41

52W Range

5.21 33.68

Valuation (TTM)

PE -1.85

PB 1.08

EV/EBITDA -0.20

Valuation (NTM)

Forward PE N/A

Forward PEG 0.48

Price Target $20

Cash Flow

FCF Yield -46.7%

SBC Adj. FCF Yield -51.5%

SBC Impact -10.3%

Margins

Gross Margin 98.5%

Operating Margin -5382.6%

FCF Margin -4317.4%

Growth (CAGR)

Revenue 3Y | 5Y 33.0% | N/A

Dil EPS 3Y | 5Y -46.4% | N/A

FCF 3Y | 5Y -61.8% | N/A

Returns

ROA -55.7%

ROE -48.4%

ROIC -62.5%

Financial Health

Net Cash

$260.35M

Current Ratio 27.99

Interest Coverage 0.00

Dividends

Div Yield N/A

Payout Ratio N/A

FCF Payout Ratio N/A

All Key Statistics

Loading financial charts...

Profile

Upstream Bio, Inc. is a biotechnology company in the clinical development stage, dedicated to innovating therapies for inflammatory conditions, particularly those affecting the severe respiratory syst...

Sector Healthcare

Industry Biotechnology

Employees 75

IPO Date Oct 10, 2024

Website upstreambio.com

Fiscal Year January - December

Full Company Profile

Latest News

No news articles available yet.

Earnings

Next Earnings

Nov 4, 2026

EPS Est

Pro

Rev Est

Pro

Earnings Details ➞

Analyst Summary

# of Analysts

Consensus

Buy

Price Target

$20

Upside

+272.44%

Buy (3)

Hold (1)

Sell (0)

Analyst Details ➞