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Spyre Therapeutics Inc.

SYRE | NASDAQ
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$90.20
-$1.83 (-1.99%)
Sep 22, 2026, 9:30 AM ET · Market open

Institutional Ownership

Net Inflow
Dollar & Volume Weighted
Total Institutions
201
Total Ownership
105.26%
Capital Flow
+$1.51B
Shares Change
+1.7M
Ownership Distribution
Institutions (99.99%)
Others (0.01%)

Institutional Sentiment

Overall: bullish
Equity Sentiment & Activity
bullish
New Positions
58
Increased Positions
123
Reduced Positions
51
Closed Positions
13
New (58)
Increased (123)
Reduced (51)
Closed (13)
Options Sentiment & Activity
bullish
Put/Call Ratio
0.088
Call Flow
324,200
Put Flow
28,400
Calls (92%)
Puts (8%)

Super Investors

Super Investor / Fund Ownership Portfolio Weight Shares Market Value
Tudor Investment Corp ET AL
< 0.01%
-68.38%
< 0.01%
2.65K
243.42K

Top Shareholders

Institution Ownership Portfolio Weight Shares Market Value
FMR LLC
15.00%
+345.93%
0.03%
+61.01%
11.78M
+1.22%
594.23M
+55.85%
Blackrock, Inc.
7.03%
+340.48%
< 0.01%
+59.13%
5.52M
-0.02%
278.49M
+53.94%
Rtw Investments, LP
5.31%
+340.55%
2.09%
+52.95%
4.17M
0.00%
210.44M
+53.97%
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