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Spyre Therapeutics Inc.

SYRE | NASDAQ
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$92.08
+$0.05 (+0.05%)
Sep 22, 2026, 10:42 AM ET · Market open
+0.05%

Rating

Updated: Aug 18, 2026
29.1
Fundamentals Weak
Market Sentiment Bullish
Moat None

Key Statistics

Market Data

Market Cap $8B
1D Range
89.90 93.58
52W Range
15.11 110.18

Valuation (TTM)

PE -47.19
PB 7.26
EV/EBITDA -36.90

Valuation (NTM)

Forward PE N/A
Forward PEG -1.49
Price Target $111.82
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Profile

Spyre Therapeutics, Inc. is a biotechnology firm operating at the preclinical stage, dedicated to creating innovative treatments for individuals afflicted with inflammatory bowel disease (IBD). Among ...

Sector Healthcare
Industry Biotechnology
Employees 125
IPO Date Apr 6, 2016
Fiscal Year January - December

Latest News

California State Teachers Retirement System Buys 5,683,670 Shares of Spyre Therapeutics, Inc. $SYRE

7 days ago · defenseworld.net

California State Teachers Retirement System Buys 5,683,670 Shares of Spyre Therapeutics, Inc. $SYRE
Spyre Therapeutics, Inc. (SYRE) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

13 days ago · seekingalpha.com

Spyre Therapeutics, Inc. (SYRE) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript
Spyre's Anti-IL-23 Antibody Meets Goal in Ulcerative Colitis Study

13 days ago · zacks.com

Spyre's Anti-IL-23 Antibody Meets Goal in Ulcerative Colitis Study
Spyre Therapeutics Announces Grants of Inducement Awards

18 days ago · globenewswire.com

Spyre Therapeutics Announces Grants of Inducement Awards
Spyre Therapeutics to Participate in Upcoming September Investor Conferences

19 days ago · globenewswire.com

Spyre Therapeutics to Participate in Upcoming September Investor Conferences
Spyre Therapeutics (SYRE) Down 16.6% Since Last Earnings Report: Can It Rebound?

19 days ago · zacks.com

Spyre Therapeutics (SYRE) Down 16.6% Since Last Earnings Report: Can It Rebound?
SYRE Stock Sinks After Mixed SKYWAY Study Data in Rheumatoid Arthritis

27 days ago · zacks.com

SYRE Stock Sinks After Mixed SKYWAY Study Data in Rheumatoid Arthritis
Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles

27 days ago · benzinga.com

Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles
Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-study of the SKYWAY Phase 2 Trial of SPY072

28 days ago · globenewswire.com

Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-study of the SKYWAY Phase 2 Trial of SPY072
Is SYRE a Buy Now as Clinical Catalysts Clash With Valuation Risk?

29 days ago · zacks.com

Is SYRE a Buy Now as Clinical Catalysts Clash With Valuation Risk?

Analyst Summary

# of Analysts
13
Consensus
Buy
Price Target
$116
Upside
+25.98%
Buy (12)
Hold (1)
Sell (0)
Analyst Details

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