Spruce Biosciences Inc.

SPRB | NASDAQ

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$53.66

-$0.04 (-0.07%)

Sep 22, 2026, 1:59 PM ET · Market open

Overview Rating Statistics Financials Earnings Analysts Ownership Profile

Market Data

Market Cap $147.8M

Enterprise Value $54.25M

Beta 3.36

Average Volume 65.2K

Shares Outstanding (Diluted) 2.43M

Shares Change YoY 300.97%

Institutional Ownership 53.92%

Exchange NASDAQ

ISIN US85209E2081

Price Performance

Price Change 1M 0.4%

Price Change 3M 3.0%

Price Change 6M -23.3%

Price Change YTD -40.8%

Price Change 1Y 491.4%

Price Change 3Y -69.9%

Price Change 5Y -88.6%

1M CAGR (ann.) 14.6%

1Y CAGR (ann.) 504.7%

5Y CAGR (ann.) -37.5%

All-Time CAGR -41.3%

Valuation

PE Ratio -1.31

Forward PE 73.38

PEG Ratio -0.02

Forward PEG 0.01

PS Ratio N/A

Forward PS 1.90

PB Ratio 1.77

P/FCF Ratio -3.46

P/Adj. FCF Ratio -3.18

P/OCF Ratio -3.06

EV/Sales N/A

EV/EBIT -1.09

EV/EBITDA -1.11

EV/FCF -1.27

Earnings Yield -76.1%

FCF Yield -28.9%

Adj. FCF Yield -31.4%

Financial Health

Net Cash $93.55M

Total Debt $2.75M

Cash & Short-Term Investments $96.3M

Total Assets $102.85M

Current Ratio 9.23

Quick Ratio 9.23

Debt / Equity Ratio 0.09

Debt / EBITDA -0.06

Debt / FCF -0.06

OCF / Debt -15.53

Interest Coverage -26.63

Altman Z-Score -0.23

Piotroski F-Score 3

Margins & Profitability

Gross Profit Margin 0.0%

Operating Profit Margin 0.0%

EBITDA Margin 0.0%

Net Profit Margin 0.0%

FCF Margin N/A

Adj. FCF Margin N/A

SBC / Revenue 0.0%

SBC Impact (per share) -8.6%

Returns

Return on Assets -49.9%

Return on Equity -123.5%

Return on Invested Capital -50.5%

Return on Capital Employed -52.0%

Return on Tangible Assets -49.9%

Historical Growth (CAGR)

Revenue CAGR 3Y -132.1%

Revenue CAGR 5Y -9.4%

Revenue CAGR 10Y N/A

EPS CAGR 3Y 27.0%

EPS CAGR 5Y 8.2%

EPS CAGR 10Y N/A

FCF CAGR 3Y 7.1%

FCF CAGR 5Y -6.9%

FCF CAGR 10Y N/A

Analyst Forecasts

Analyst Rating Buy

Analyst Count 11

EPS Growth Next 3Y 30.7%

Revenue Growth Next 3Y N/A

Earnings Date Nov 8, 2026

EPS Estimate (next Q) -$5.68

EPS Growth Est (next Q) -61.1%

Revenue Est (next Q) $50M

Revenue Growth Est (next Q) N/A

Fair Value Estimates

Graham Number N/A

Graham Upside N/A

Lynch Fair Value N/A

Lynch Upside N/A

Price Target $135.75

Price Target Upside 152.8%

Cash Flow

Operating Cash Flow $-42.62M

Free Cash Flow $-42.77M

Adj. Free Cash Flow $-46.44M

FCF Per Share -$17.59

OCF Per Share -$17.53

OCF/S Ratio 0.0%

Income Statement

Revenue $0

Gross Profit $0

Operating Income $-47.83M

EBITDA $-48.67M

Net Income $-51.35M

EPS (Diluted) -$40.87

Revenue / Employee N/A

Profit / Employee $-2.33M

Employees 22