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    • Denali Therapeutics Inc. logo

    Denali Therapeutics Inc.

    DNLI | NASDAQ
    Chart Builder DCF Calculator
    $20.47
    +$0.75 (+3.80%)
    At close: Sep 21, 2026, 4:00 PM ET
    $20.52
    +$0.05 (+0.24%)
    Pre-market: Sep 22, 2026, 5:34 AM ET
    Overview Rating Statistics Financials Earnings Analysts Ownership Profile

    Market Data

    Market Cap
    $3.13B
    Enterprise Value
    $2.57B
    Beta
    1.01
    Average Volume
    1.73M
    Shares Outstanding (Diluted)
    187.31M
    Shares Change YoY
    9.25%
    Institutional Ownership
    78.98%
    Exchange
    NASDAQ
    ISIN
    US24823R1059

    Price Performance

    Price Change 1M
    -18.3%
    Price Change 3M
    -17.4%
    Price Change 6M
    -8.9%
    Price Change YTD
    25.8%
    Price Change 1Y
    53.7%
    Price Change 3Y
    -7.6%
    Price Change 5Y
    -59.9%
    1M CAGR (ann.)
    -20.3%
    1Y CAGR (ann.)
    51.0%
    5Y CAGR (ann.)
    -17.5%
    All-Time CAGR
    -0.9%

    Valuation

    PE Ratio
    -7.21
    Forward PE
    N/A
    PEG Ratio
    4.06
    Forward PEG
    -2.89
    PS Ratio
    901.44
    Forward PS
    25.10
    PB Ratio
    3.89
    P/FCF Ratio
    -5.69
    P/Adj. FCF Ratio
    -4.89
    P/OCF Ratio
    -8.82
    EV/Sales
    711.94
    EV/EBIT
    -6.69
    EV/EBITDA
    -5.09
    EV/FCF
    -4.49
    Earnings Yield
    -13.9%
    FCF Yield
    -17.6%
    Adj. FCF Yield
    -20.4%

    Financial Health

    Net Cash
    $710.47M
    Total Debt
    $27.51M
    Cash & Short-Term Investments
    $710.47M
    Total Assets
    $1.16B
    Current Ratio
    8.37
    Quick Ratio
    8.32
    Debt / Equity Ratio
    0.03
    Debt / EBITDA
    -0.05
    Debt / FCF
    -0.05
    OCF / Debt
    -20.55
    Interest Coverage
    0.00
    Altman Z-Score
    2.63
    Piotroski F-Score
    2

    Margins & Profitability

    Gross Profit Margin
    -61.0%
    Operating Profit Margin
    -15058.2%
    EBITDA Margin
    -13798.3%
    Net Profit Margin
    -14191.2%
    FCF Margin
    -15847.0%
    Adj. FCF Margin
    -18428.6%
    SBC / Revenue
    1941.0%
    SBC Impact (per share)
    -16.3%

    Returns

    Return on Assets
    -44.2%
    Return on Equity
    -55.3%
    Return on Invested Capital
    -50.8%
    Return on Capital Employed
    -50.8%
    Return on Tangible Assets
    -45.6%

    Historical Growth (CAGR)

    Revenue CAGR 3Y
    -78.1%
    Revenue CAGR 5Y
    -60.1%
    Revenue CAGR 10Y
    0.3%
    EPS CAGR 3Y
    0.2%
    EPS CAGR 5Y
    -11.7%
    EPS CAGR 10Y
    9.8%
    FCF CAGR 3Y
    -18.9%
    FCF CAGR 5Y
    -19.0%
    FCF CAGR 10Y
    -31.4%

    Analyst Forecasts

    Analyst Rating
    Buy
    Analyst Count
    19
    EPS Growth Next 3Y
    20.5%
    Revenue Growth Next 3Y
    396.4%
    Earnings Date
    Nov 4, 2026
    EPS Estimate (next Q)
    -$0.37
    EPS Growth Est (next Q)
    -49.9%
    Revenue Est (next Q)
    $12.22M
    Revenue Growth Est (next Q)
    N/A

    Fair Value Estimates

    Graham Number
    N/A
    Graham Upside
    N/A
    Lynch Fair Value
    N/A
    Lynch Upside
    N/A
    Price Target
    $33.67
    Price Target Upside
    64.5%

    Cash Flow

    Operating Cash Flow
    $-565.24M
    Free Cash Flow
    $-571.13M
    Adj. Free Cash Flow
    $-664.17M
    FCF Per Share
    -$2.34
    OCF Per Share
    -$2.32
    OCF/S Ratio
    -12043.3%

    Income Statement

    Revenue
    $3.6M
    Gross Profit
    $-5.71M
    Operating Income
    $-542.7M
    EBITDA
    $-503.85M
    Net Income
    $-511.45M
    EPS (Diluted)
    -$2.84
    Revenue / Employee
    $7.17K
    Profit / Employee
    $-1.02M
    Employees
    503

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